2 edition of Epidemiological studies of congenital cytomegalovirus infection found in the catalog.
Epidemiological studies of congenital cytomegalovirus infection
Bibliography: p. 30-35.
|Statement||by Karin Ahlfors.|
|Series||Scandinavian journal of infectious diseases. Supplementum -- 34, Scandinavian journal of infectious diseases -- 34.|
|The Physical Object|
|Pagination||36 p. ;|
|Number of Pages||36|
Currently there is no evidence of benefit of antiviral therapy in asymptomatic infants, since they were not included in any of the above mentioned studies, and therefore asymptomatic infants should not receive antiviral therapy. Antibody tests cannot be used to diagnose congenital CMV; a diagnosis can only be made if the virus is detected during the first week of life. Screening programs, both in pregnant women and in newborns, have not been developed or implemented. Acute acquired CMV infection. Conclusions Congenital CMV infection is responsible of a high burden of disease worldwide. Women carrying fetuses without signs of infection and fetuses with severe ultrasound brain abnormalities were excluded.
These risks appear to be almost exclusively associated with women who previously have not been infected with CMV and who are having their first infection with the virus during pregnancy. Treatment with antiviral medicines is often used for infants with neurologic nervous system symptoms. Preventive strategies other than behavioral measures during pregnancy are still lacking, but there is great research interest focused on the field. Screening methods, which only aim to identify women with primary infection during pregnancy, may be overlooking these cases.
The application of real-time PCR on urine collected by using other strategies, such as cotton balls or filter cards in diapers, has not been evaluated in large, population-based screening programs and has not been compared with a gold-standard diagnostic method [ 3637 ]. Beside neutropenia, there is evidence of carcinogenicity and gonadotoxicity of GCV in some animal models, although no such toxicities have been demonstrated in humans at this time. Preview Unable to display preview. In immunocompromised hosts and infected fetuses, though, CMV produces a high burden of disease.
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Nutley, N. Philadelphia, PA: Elsevier Saunders; chap These results show that standard maternal screening methods which pinpoint pregnant women who have primary CMV infection during pregnancy can only predict 3 cases with congenital infection, and the remaining 7 cases were overlooked.
Management of acute otitis media. The content is provided for information purposes only. Population Epidemiological studies of congenital cytomegalovirus infection book of ganciclovir in newborns with congenital cytomegalovirus infections.
Early detection and intervention for children with hearing and vision problems may improve outcomes. Most infants with congenital CMV grow up healthy. However, the diagnostic criteria of symptomatic infection vary widely in the literature.
Warn immunodeficient patients and pregnant women to avoid any individuals with confirmed or suspected CMV infection. There appears to be little risk of CMV-related complications for women who have been infected at least 6 months prior to conception. Explore further More information: Kenji Tanimura et al.
Epidemiologic characteristics of cytomegalovirus infection in mothers and their infants. Prevention of child-to-mother transmission of cytomegalovirus by changing behaviors: A randomized controlled trial. The demonstrated benefits of breast-feeding outweigh the minimal risk of acquiring CMV from the breast-feeding mother.
Women carrying fetuses without signs of infection and fetuses with severe ultrasound brain abnormalities were excluded.
Further studies are urgently needed to clarify the utility of blood viral load as a predictor of SNHL.
Nelson Textbook of Pediatrics. Contact can be minimized by using gloves or other protective barriers when handling body fluids or contaminated Epidemiological studies of congenital cytomegalovirus infection book such as diapers or tissuesavoiding shared dishes, utensils, and other personal items, and consistent and thorough hand-washing.
Agents Chemother. Vestibular impairment also has been reported frequently, and possibly can show progressive deterioration over time [ 24 ]. In order to identify all infants with congenital CMV infection upon birth, there are limitations to the current screening methods used for pregnant women.
Studies have shown that these counselling-based interventions for CMV seronegative women may be effective in reducing CMV transmission [ 4950 ], and it is conceivable that limiting exposure to CMV could benefit also CMV seropositive women.
The presentation in this latter group is a continuum of disease expression whose more common findings are petechiae, jaundice, hepatomegaly, splenomegaly, microcephaly, and other neurologic signs.This supplement consists of a doctoral dissertation by Dr Áhlfors in which she presents the results of a very extensive investigation of congenital cytomegalovirus (CMV) infection occurring in Malmö, Sweden.
A wealth of epidemiological information is presented which will be of great value to any reader interested in congenital infection.
The most productive study referred to was a prospective Cited by: Congenital cytomegalovirus infection (CMV) is the commonest congenital infec-tion affecting from % to % of all live births. Approximately 10% of in-fected infants manifest significant clinical illness in the newborn period with a variety of manifestations, including poor growth, microcephaly, jaundice.
Apr 17, · Epidemiological studies of congenital cytomegalovirus infection book (CMV) is the most frequent cause of congenital infection worldwide, with an estimated incidence in developed countries of –% of all live births.
The burden of disease related to congenital CMV in substantial, as it is the leading non-genetic cause of sensorineural hearing loss and an important cause of neurodevelopmental disabilities in children.
Despite its clinical Cited by: Congenital cytomegalovirus (CMV) infection is the most common intrauterine transmitted viral infection, pdf a tremendous impact on fetuses and newborns.
In this book the history of this disease, its pathophysiological background, epidemiology and symptoms, as well as diagnostic and therapeutic strategies, will be discussed.Mar 31, · Congenital cytomegalovirus (CMV) infection is the most common intrauterine transmitted viral infection, with a tremendous impact on fetuses and newborns.
In this book the history of this disease, its pathophysiological background, epidemiology and symptoms, as well as diagnostic and therapeutic strategies, will be discussed.Congenital Cytomegalovirus Infection: Hearing Loss Characteristics, Ebook Management, and Fostering Parent Partnerships Faye P.
McCollister, EdD, CCC-A, CED Associate Professor Emeritus, University of Alabama Audiology Consultant, National Center for Hearing Assessment and Management Audiology Consultant, UAB CHIMES Study.